Contraindicated (one)bortezomib will increase the level or impact of mavacamten by affecting hepatic enzyme CYP2C19 metabolism. Contraindicated. Powerful or moderate CYP2C19 inhibitors might improve mavacamten systemic publicity, leading to heart failure because of systolic dysfunction.

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This is not a whole listing of attainable side effects. When you discover other outcomes not shown over, Call your health practitioner or pharmacist.

bortezomib will enhance the amount or effect of diazepam intranasal by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Check. Sturdy or average CYP2C19 inhibitors may reduce fee of diazepam elimination, thus increasing adverse reactions to diazepam.

Contraindicated (one)bortezomib raises amounts of eliglustat by affecting hepatic enzyme CYP2D6 metabolism. Contraindicated. If coadministered with potent or reasonable CYP2D6 inhibitors, reduce eliglustat dose from eighty four mg BID to eighty four mg the moment daily in considerable and intermediate metabolizers; eliglustat is contraindiated if sturdy or average CYP2D6 inhibitors are provided concomitantly with robust or reasonable CYP3A inhibitors.

triclabendazole will improve the level or influence of bortezomib by impacting hepatic enzyme CYP2C19 metabolism.

etravirine will lower the level or impact of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

Prescription drugs are frequently analyzed to discover if they could assistance treat or reduce circumstances aside from the ones They are really approved for. This affected person data sheet applies only to authorised uses from the drug. On the other hand, A great deal of the data could also use to unapproved employs that are now being researched.

bortezomib will raise the level or outcome of ruxolitinib CDK4/6-IN-6 by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.

Posterior reversible encephalopathy syndrome, PRES (formerly RPLS); basic safety of reinitiating therapy in people Beforehand encountering PRES is not really recognized

eslicarbazepine acetate will improve the amount or effect of bortezomib by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep an eye on.

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etravirine will minimize the extent 2' or result of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

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